Contents‎ > ‎

Original Articles

Last update 2018/08/18


282) Directed strain evolution restructures metabolism for 1-butanol production in minimal media.
Pontrelli S, Fricke RCB, Sakurai SSM, Putri SP, Fitz-Gibbon S, Chung M, Wu HY, Chen YJ, Pellegrini M, Fukusaki E, Liao JC.
Metab Eng. 2018 Aug 11. pii: S1096-7176(18)30197-6. doi: 10.1016/j.ymben.2018.08.004. [Epub ahead of print]

281) Identification of Metabolites Associated with Onset of CAD in Diabetic Patients Using CE-MS Analysis: A Pilot Study.
Omori K, Katakami N, Yamamoto Y, Ninomiya H, Takahara M, Matsuoka TA, Bamba T, Fukusaki E, Shimomura I.
J Atheroscler Thromb. 2018 Aug 1. doi: 10.5551/jat.42945. [Epub ahead of print]

280) Mass spectrometric imaging of GABA in the Drosophila melanogaster adult head.
Enomoto Y, An PN, Yamaguchi M, Fukusaki E, Shimma S.
Anal Sci. 2018 Jul 27. doi: 10.2116/analsci.18SCN01. [Epub ahead of print] No abstract available.

279) Metabolomics-based profiling of three terminal alkene-producing Jeotgalicoccus spp. during different growth phase.
Nusantara Putra FJ, Putri SP, Fukusaki E.
J Biosci Bioeng. 2018 Jul 26. pii: S1389-1723(18)30244-5. doi: 10.1016/j.jbiosc.2018.06.014. [Epub ahead of print]

Anal Chem. 2018 Aug 7;90(15):9068-9076. doi: 10.1021/acs.analchem.8b01388. Epub 2018 Jul 19.

277) Iterative cycle of widely targeted metabolic profiling for the improvement of 1-butanol titer and productivity in Synechococcus elongatus.
Fathima AM, Chuang D, Laviña WA, Liao J, Putri SP, Fukusaki E.
Biotechnol Biofuels. 2018 Jul 9;11:188. doi: 10.1186/s13068-018-1187-8. eCollection 2018.

276) Identifying metabolic elements that contribute to productivity of 1-propanol bioproduction using metabolomic analysis
Sastia Prama Putri, Yasumune Nakayama, Claire Shen, Shingo Noguchi, Katsuaki Nitta, Takeshi Bamba, Sammy Pontrelli, James Liao, Eiichiro Fukusaki
Metabolomics 14 (7), 96

275) Development of a visualization method for imidacloprid in Drosophila melanogaster via imaging mass spectrometry.
Ohtsu S, Yamaguchi M, Nishiwaki H, Fukusaki E, Shimma S.
Anal Sci. 2018 Jun 29. doi: 10.2116/analsci.18SCP04. [Epub ahead of print] No abstract available.

274) Visualization of Asparaptine in Asparagus (Asparagus officinalis) using MALDI-IMS.
Miyoshi K, Enomoto Y, Fukusaki E, Shimma S.
Anal Sci. 2018 Jun 29. doi: 10.2116/analsci.18SCP03. [Epub ahead of print] No abstract available.

Nagao H, Nishizawa H, Tanaka Y, Fukata T, Mizushima T, Furuno M, Bamba T, Tsushima Y, Fujishima Y, Kita S, Funahashi T, Maeda N, Mori M, Fukusaki E, Shimomura I.
Obesity (Silver Spring). 2018 Jul;26(7):1168-1178. doi: 10.1002/oby.22202. Epub 2018 Jun 7.

272) Gas chromatography coupled with mass spectrometry-based metabolomics for the classification of tempe from different regions and production processes in Indonesia.
Kadar AD, Aditiawati P, Astawan M, Putri SP, Fukusaki E.
J Biosci Bioeng. 2018 Sep;126(3):411-416. doi: 10.1016/j.jbiosc.2018.03.020. Epub 2018 Apr 27.

271) Metabolomics approach to reduce the Crabtree effect in continuous culture of Saccharomyces cerevisiae.
Imura M, Iwakiri R, Bamba T, Fukusaki E.
J Biosci Bioeng. 2018 Aug;126(2):183-188. doi: 10.1016/j.jbiosc.2018.02.008. Epub 2018 Apr 22.

270) Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.
Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, Fujishima Y, Nagao H, Masuda S, Tanaka Y, Nakamura Y, Nishizawa H, Funahashi T, Ranscht B, Izumi Y, Bamba T, Fukusaki E, Hanayama R, Shimada S, Maeda N, Shimomura I.
JCI Insight. 2018 Apr 19;3(8). pii: 99680. doi: 10.1172/jci.insight.99680. [Epub ahead of print]

269) Molecular Components of Arabidopsis Intact Vacuoles Clarified with Metabolomic and Proteomic Analyses.
Ohnishi M, Anegawa A, Sugiyama Y, Harada K, Oikawa A, Nakayama Y, Matsuda F, Nakamura Y, Sasaki R, Shichijo C, Hatcher PG, Fukaki H, Kanaya S, Aoki K, Yamazaki M, Fukusaki E, Saito K, Mimura T.
Plant Cell Physiol. 2018 Jul 1;59(7):1353-1362. doi: 10.1093/pcp/pcy069.

268) Microbe participation in aroma production during soy sauce fermentation.
Harada R, Yuzuki M, Ito K, Shiga K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2018 Jan 20. pii: S1389-1723(17)31003-4. doi: 10.1016/j.jbiosc.2017.12.004. [Epub ahead of print]

267) Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion.
Takeuchi Y, Nakayama Y, Fukusaki E, Irino Y.
Biochem Biophys Res Commun. 2018 Jan 1;495(1):761-767. doi: 10.1016/j.bbrc.2017.11.088. Epub 2017 Nov 14.

266) Metabolic profiling of Garcinia mangostana (mangosteen) based on ripening stages.
Parijadi AAR, Putri SP, Ridwani S, Dwivany FM, Fukusaki E.
J Biosci Bioeng. 2018 Feb;125(2):238-244. doi: 10.1016/j.jbiosc.2017.08.013. Epub 2017 Sep 29.

265) Inhibition of Saccharomyces cerevisiae growth by simultaneous uptake of glucose and maltose.
Hatanaka H, Mitsunaga H, Fukusaki E.
J Biosci Bioeng. 2018 Jan;125(1):52-58. doi: 10.1016/j.jbiosc.2017.07.013. Epub 2017 Sep 15.


264) Development of a split-flow system for high precision variable sample introduction in supercritical fluid chromatography.
Sakai M, Hayakawa Y, Funada Y, Ando T, Fukusaki E, Bamba T.
J Chromatogr A. 2017 Sep 15;1515:218-231. doi: 10.1016/j.chroma.2017.07.077. Epub 2017 Jul 25.

J Biosci Bioeng. 2017 Dec;124(6):700-706. doi: 10.1016/j.jbiosc.2017.07.006. Epub 2017 Aug 8.

262) Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a.
An PNT, Shimaji K, Tanaka R, Yoshida H, Kimura H, Fukusaki E, Yamaguchi M.
Sci Rep. 2017 Aug 4;7(1):7343. doi: 10.1038/s41598-017-07566-1.

Regestein Née Meissner L, Arndt J, Palmen TG, Jestel T, Mitsunaga H, Fukusaki E, Büchs J.
J Biol Eng. 2017 Jul 12;11:23. doi: 10.1186/s13036-017-0065-4. eCollection 2017.

260) Orthogonal partial least squares/projections to latent structures regression-based metabolomics approach for identification of gene targets for improvement of 1-butanol production in Escherichia coli.
Nitta K, Laviña WA, Pontrelli S, Liao JC, Putri SP, Fukusaki E.
J Biosci Bioeng. 2017 Nov;124(5):498-505. doi: 10.1016/j.jbiosc.2017.05.015. Epub 2017 Jun 29.
Taniguchi M, Konya Y, Nakano Y, Fukusaki E.
Matsuo T, Tsugawa H, Miyagawa H, Fukusaki E.
Anal Chem. 2017 Jun 20;89(12):6766-6773. doi: 10.1021/acs.analchem.7b01010. Epub 2017 May 26.

Ohtake T, Pontrelli S, Laviña WA, Liao JC, Putri SP, Fukusaki E.
Metab Eng. 2017 May;41:135-143. doi: 10.1016/j.ymben.2017.04.003. Epub 2017 Apr 8.

Ogawa T, Izumi Y, Kusumoto K, Fukusaki E, Bamba T.
Rapid Commun Mass Spectrom. 2017 Jun 15;31(11):928-936. doi: 10.1002/rcm.7862.

254) Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status.
Sakanaka A, Kuboniwa M, Hashino E, Bamba T, Fukusaki E, Amano A.
Sci Rep. 2017 Feb 21;7:42818. doi: 10.1038/srep42818.

253) Effect of Furan Fatty Acids and 3-Methyl-2,4-Nonanedione on Light-Induced Off-Odor in Soybean Oil.
Sano T, Okabe R, Iwahashi M, Imagi J, Sato T, Yamashita T, Fukusaki E, Bamba T.
J Agric Food Chem. 2017 Mar 15;65(10):2136-2140. doi: 10.1021/acs.jafc.6b05056. Epub 2017 Feb 28.

252) In
creased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue: In vivo Metabolic Turnover Analysis.
Nagao H, Nishizawa H, Bamba T, Nakayama Y, Isozumi N, Nagamori S, Kanai Y, Tanaka Y, Kita S, Fukuda S, Funahashi T, Maeda N, Fukusaki E, Shimomura I.
J Biol Chem. 2017 Mar 17;292(11):4469-4483. doi: 10.1074/jbc.M116.770172. Epub 2017 Jan 24.

251) Lipoprotein profiling methodology based on determination of apolipoprotein concentration.
Takeda H, Izumi Y, Tomita A, Koike T, Shiomi M, Fukusaki E, Matsuda F, Bamba T.
Bioanalysis. 2017 Jan;9(1):9-19.

250) Simultaneous profiling of 17 steroid hormones for the evaluation of endocrine-disrupting chemicals in H295R cells.
Jumhawan U, Yamashita T, Ishida K, Fukusaki E, Bamba T.
Bioanalysis. 2017 Jan;9(1):67-69.

Harada R, Yuzuki M, Ito K, Shiga K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2017 Feb;123(2):203-208. doi: 10.1016/j.jbiosc.2016.08.010. Epub 2016 Dec 7.

Konya Y, Taniguchi M, Fukusaki E.
J Biosci Bioeng. 2017 Jan;123(1):126-133. doi: 10.1016/j.jbiosc.2016.07.009. Epub 2016 Sep 17.

247) Metabolic engineering for isopropanol production by an engineered cyanobacterium, Synechococcus elongatus PCC 7942, under photosynthetic conditions.
Hirokawa Y, Dempo Y, Fukusaki E, Hanai T.
J Biosci Bioeng. 2017 Jan;123(1):39-45. doi: 10.1016/j.jbiosc.2016.07.005.

246) Quality evaluation of green tea leaf cultured under artificial light condition using gas chromatography/mass spectrometry.
Miyauchi S, Yonetani T, Yuki T, Tomio A, Bamba T, Fukusaki E.
J Biosci Bioeng. 2017 Feb;123(2):197-202. doi: 10.1016/j.jbiosc.2016.07.017.

Nakano Y, Konya Y, Taniguchi M, Fukusaki E.
J Biosci Bioeng. 2017 Jan;123(1):134-138. doi: 10.1016/j.jbiosc.2016.07.008.


244) Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network.
Moriyama T, Tanaka S, Nakayama Y, Fukumoto M, Tsujimura K, Yamada K, Bamba T, Yoneda Y, Fukusaki E, Oka M.
Sci Rep. 2016 Oct 5;6:34648. doi: 10.1038/srep34648.

243) Prediction of Periodontal Inflammation via Metabolic Profiling of Saliva.
Kuboniwa M, Sakanaka A, Hashino E, Bamba T, Fukusaki E, Amano A.
J Dent Res. 2016 Nov;95(12):1381-1386. doi: 10.1177/0022034516661142.
Mitsunaga H, Meissner L, Büchs J, Fukusaki E.
J Biosci Bioeng. 2016 Oct;122(4):400-5. doi: 10.1016/j.jbiosc.2016.03.007. Epub 2016 May 18.

241) A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis.
Chun S, Bamba T, Suyama T, Ishijima T, Fukusaki E, Abe K, Nakai Y.
PLoS One. 2016 May 17;11(5):e0155386. doi: 10.1371/journal.pone.0155386. eCollection 2016.

240) Relationship between 3-Methyl-2,4-nonanedione Concentration and Intensity of Light-induced Off-odor in Soy Bean Oil.

Sano T, Iwahashi M, Imagi J, Sato T, Yamashita T, Fukusaki E, Bamba T.

J Oleo Sci. 2016 May 1;65(5):447-50. doi: 10.5650/jos.ess15233. Epub 2016 Apr 15.

 In vitro steroid profiling system for the evaluation of endocrine disruptors.
Nakano Y, Yamashita T, Okuno M, Fukusaki E, Bamba T.
J Biosci Bioeng. 2016 Sep;122(3):370-7. doi: 10.1016/j.jbiosc.2016.02.008. Epub 2016 Mar 12.

238) Random Sample Consensus combined with Partial Least Squares regression (RANSAC-PLS) for microbial metabolomics data mining and phenotype improvement.
Teoh ST, Kitamura M, Nakayama Y, Putri S, Mukai Y, Fukusaki E.
J Biosci Bioeng. 2016 Aug;122(2):168-75. doi: 10.1016/j.jbiosc.2016.01.007. Epub 2016 Feb 6.
Hori K, Hori-Koriyama N, Tsumura K, Fukusaki E, Bamba T.
J Biosci Bioeng. 2016 Aug;122(2):246-51. doi: 10.1016/j.jbiosc.2015.12.018. Epub 2016 Jan 25.

236) Method for the Compound Annotation of Conjugates in Nontargeted Metabolomics Using Accurate Mass Spectrometry, Multistage Product Ion Spectra and Compound Database Searching.
Ogura T, Bamba T, Tai A, Fukusaki E.
Mass Spectrom (Tokyo). 2015;4(1):A0036. doi: 10.5702/massspectrometry.A0036. Epub 2015 Mar 26.

235) Quantification of coffee blends for authentication of Asian palm civet coffee (Kopi Luwak) via metabolomics: A proof of concept.

Jumhawan U, Putri SP, Yusianto, Bamba T, Fukusaki E.

J Biosci Bioeng. 2016 Jul;122(1):79-84. doi: 10.1016/j.jbiosc.2015.12.008. Epub 2016 Jan 6.

234) Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production.
Noguchi S, Putri SP, Lan EI, Laviña WA, Dempo Y, Bamba T, Liao JC, Fukusaki E.
Metabolomics. 2016;12:26. Epub 2016 Jan 4.


233) A particular silent codon exchange in a recombinant gene greatly influences host cell metabolic activity.
Rahmen N, Schlupp CD, Mitsunaga H, Fulton A, Aryani T, Esch L, Schaffrath U, Fukuzaki E, Jaeger KE, Büchs J. 
Microb Cell Fact. 2015 Oct 5;14(1):156. doi: 10.1186/s12934-015-0348-8.

232) Metabolome analysis reveals the effect of carbon catabolite control on the poly(γ-glutamic acid) biosynthesis of Bacillus licheniformis ATCC 9945.

Mitsunaga H, Meissner L, Palmen T, Bamba T, Büchs J, Fukusaki E.

J Biosci Bioeng. 2016 Apr;121(4):413-9. doi: 10.1016/j.jbiosc.2015.08.012. Epub 2015 Sep 26.

231) Profiling of volatile compounds in APCMin/+ mice blood by dynamic headspace extraction and gas chromatography/mass spectrometry.

Kakuta S, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 15;1003:35-40. doi: 10.1016/j.jchromb.2015.09.002. Epub 2015 Sep 11.

230) A metabolomics-based strategy for identification of gene targets for phenotype improvement and its application to 1-butanol tolerance in Saccharomyces cerevisiae.
Teoh ST, Putri S, Mukai Y, Bamba T, Fukusaki E.
Biotechnol Biofuels. 2015 Sep 15;8:144. doi: 10.1186/s13068-015-0330-z. eCollection 2015.

229) Metabolomic approach for improving ethanol stress tolerance in Saccharomyces cerevisiae.

Ohta E, Nakayama Y, Mukai Y, Bamba T, Fukusaki E.

J Biosci Bioeng. 2016 Apr;121(4):399-405. doi: 10.1016/j.jbiosc.2015.08.006. Epub 2015 Sep 3.

228) Extra-facile chiral separation of amino acid enantiomers by LC-TOFMS analysis.

Konya Y, Bamba T, Fukusaki E.

J Biosci Bioeng. 2016 Mar;121(3):349-53. doi: 10.1016/j.jbiosc.2015.06.017. Epub 2015 Aug 28.

227) Lipidomic analysis of plasma lipoprotein fractions in myocardial infarction-prone rabbits.

Takeda H, Koike T, Izumi Y, Yamada T, Yoshida M, Shiomi M, Fukusaki E, Bamba T.

J Biosci Bioeng. 2015 Oct;120(4):476-82. doi: 10.1016/j.jbiosc.2015.02.015. Epub 2015 Jul 8.

226) Influence of nitrogen source and pH value on undesired poly(γ-glutamic acid) formation of a protease producing Bacillus licheniformis strain.
Meissner L, Kauffmann K, Wengeler T, Mitsunaga H, Fukusaki E, Büchs J.
J Ind Microbiol Biotechnol. 2015 Sep;42(9):1203-15. doi: 10.1007/s10295-015-1640-7. Epub 2015 Jul 8.

225) New Insight into the Role of the Calvin Cycle: Reutilization of CO2 Emitted through Sugar Degradation.
Shimizu R, Dempo Y, Nakayama Y, Nakamura S, Bamba T, Fukusaki E, Fukui T.
Sci Rep. 2015 Jul 1;5:11617. doi: 10.1038/srep11617.

224) Application of gas chromatography/flame ionization detector-based metabolite fingerprinting for authentication of Asian palm civet coffee (Kopi Luwak).
Jumhawan U, Putri SP, Yusianto, Bamba T, Fukusaki E.
J Biosci Bioeng. 2015 Nov;120(5):555-61. doi: 10.1016/j.jbiosc.2015.03.005. Epub 2015 Apr 23.
Wakabayashi T, Joseph B, Yasumoto S, Akashi T, Aoki T, Harada K, Muranaka S, Bamba T, Fukusaki E, Takeuchi Y, Yoneyama K, Muranaka T, Sugimoto Y, Okazawa A.
J Exp Bot. 2015 Jun;66(11):3085-97. doi: 10.1093/jxb/erv116. Epub 2015 Mar 28.

Tsugawa H, Ohta E, Izumi Y, Ogiwara A, Yukihira D, Bamba T, Fukusaki E, Arita M.
Front Genet. 2015 Jan 30;5:471. doi: 10.3389/fgene.2014.00471. eCollection 2014.
Mass Spectrom (Tokyo). 2015;4(1):A0034. doi: 10.5702/massspectrometry.A0034. Epub 2015 Jan 15.

220) Lansioside D, a new triterpenoid glycoside antibiotic from the fruit peel of Lansium domesticum Correa
EC Marfori, SI Kajiyama, EI Fukusaki, A Kobayashi
Journal of Pharmacognosy and Phytochemistry 3 (5), 140-143

219) High-Throughput Simultaneous Analysis of Pesticides by Supercritical Fluid Chromatography Coupled with High-Resolution Mass Spectrometry.
Ishibashi M, Izumi Y, Sakai M, Ando T, Fukusaki E, Bamba T.
J Agric Food Chem. 2015 May 13;63(18):4457-63. doi: 10.1021/jf5056248. Epub 2015 Jan 16.

218) Bulk RNA degradation by nitrogen starvation-induced autophagy in yeast.
Huang H, Kawamata T, Horie T, Tsugawa H, Nakayama Y, Ohsumi Y, Fukusaki E.
EMBO J. 2015 Jan 14;34(2):154-68. doi: 10.15252/embj.201489083. Epub 2014 Dec 2.

Taguchi K, Fukusaki E, Bamba T.
Mass Spectrom (Tokyo). 2014;3(1):A0029. doi: 10.5702/massspectrometry.A0029. Epub 2014 Aug 1.

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion.
Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S.
Cell Rep. 2014 Oct 23;9(2):661-73. doi: 10.1016/j.celrep.2014.09.030. Epub 2014 Oct 16.

215) Changes in transcription and metabolism during the early stage of replicative cellular senescence in budding yeast.
Kamei Y, Tamada Y, Nakayama Y, Fukusaki E, Mukai Y.
J Biol Chem. 2014 Nov 14;289(46):32081-93. doi: 10.1074/jbc.M114.600528. Epub 2014 Oct 7.
Nakayama Y, Tamada Y, Tsugawa H, Bamba T, Fukusaki E.
Metabolites. 2014 Aug 25;4(3):722-39. doi: 10.3390/metabo4030722.

213) Simultaneous analysis for water- and fat-soluble vitamins by a novel single chromatography technique unifying supercritical fluid chromatography and liquid chromatography.
Taguchi K, Fukusaki E, Bamba T.
J Chromatogr A. 2014 Oct 3;1362:270-7. doi: 10.1016/j.chroma.2014.08.003. Epub 2014 Aug 12.

212) Supercritical fluid extraction as a preparation method for mass spectrometry of dried blood spots.
Matsubara A, Izumi Y, Nishiumi S, Suzuki M, Azuma T, Fukusaki E, Bamba T, Yoshida M.
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 17;969C:199-204. doi: 10.1016/j.jchromb.2014.08.013. [Epub ahead of print]

211) Metabolome Analysis of Drosophila melanogaster during Embryogenesis.
An PN, Yamaguchi M, Bamba T, Fukusaki E.
PLoS One. 2014 Aug 14;9(8):e99519. doi: 10.1371/journal.pone.0099519. eCollection 2014.

210) Gas chromatography/mass spectrometry based component profiling and quality prediction for Japanese sake.
Mimura N, Isogai A, Iwashita K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Oct;118(4):406-14. doi: 10.1016/j.jbiosc.2014.04.006. Epub 2014 Jul 22.

209) Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity.
Rahman M, Nirala NK, Singh A, Zhu LJ, Taguchi K, Bamba T, Fukusaki E, Shaw LM, Lambright DG, Acharya JK, Acharya UR.
J Cell Biol. 2014 Jul 21;206(2):289-305. doi: 10.1083/jcb.201404118. Epub 2014 Jul 14.

208) Metabolic profiling of retrograde pathway transcription factors rtg1 and rtg3 knockout yeast.
Hashim Z, Mukai Y, Bamba T, Fukusaki E.
Metabolites. 2014 Jul 8;4(3):580-98. doi: 10.3390/metabo4030580.

Hashim Z, Teoh ST, Bamba T, Fukusaki E.
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:83-92. doi: 10.1016/j.jchromb.2014.05.041. Epub 2014 May 27.

Shiga K, Yamamoto S, Nakajima A, Kodama Y, Imamura M, Sato T, Uchida R, Obata A, Bamba T,Fukusaki E.
J Agric Food Chem. 2014 Jul 23;62(29):7317-22. doi: 10.1021/jf501173r. Epub 2014 Jul 11.

204) High-quality green tea leaf production by artificial cultivation under growth chamber conditions considering amino acids profile.
Miyauchi S, Yuki T, Fuji H, Kojima K, Yonetani T, Tomio A, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Dec;118(6):710-5. doi: 10.1016/j.jbiosc.2014.05.008. Epub 2014 Jun 7.

 Metabolic distance estimation based on principle component analysis of metabolic turnover.
Nakayama Y, Putri SP, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Sep;118(3):350-5. doi: 10.1016/j.jbiosc.2014.02.014. Epub 2014 Mar 26.

Lee JW, Nagai T, Gotoh N, Fukusaki E, Bamba T.
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Sep 1;966:193-9. doi: 10.1016/j.jchromb.2014.01.040. Epub 2014 Feb 3.

201) Practical evaluation of liquid chromatography/tandem mass spectrometry and enzyme immunoassay method for the accurate quantitative analysis of prostaglandins.
Izumi Y, Aritake K, Urade Y, Fukusaki E.
J Biosci Bioeng. 2014 Jul;118(1):116-8. doi: 10.1016/j.jbiosc.2013.12.022. Epub 2014 Feb 16.

200) Analysis of the correlation between dipeptides and taste differences among soy sauces by using metabolomics-based component profiling.

Yamamoto S, Shiga K, Kodama Y, Imamura M, Uchida R, Obata A, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Jul;118(1):56-63. doi: 10.1016/j.jbiosc.2013.12.019. Epub 2014 Feb 1.

199) c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions.
Kajiwara K, Yamada T, Bamba T, Fukusaki E, Imamoto F, Okada M, Oneyama C.
Biochem J. 2014 Feb 15;458(1):81-93. doi: 10.1042/BJ20130527.

198) Cloning and functional analysis of HpFAD2 and HpFAD3 genes encoding Δ12- and Δ15-fatty acid desaturases in Hansenula polymorpha.
Sangwallek J, Kaneko Y, Tsukamoto T, Marui M, Sugiyama M, Ono H, Bamba T, Fukusaki E, Harashima S.
Gene. 2014 Jan 1;533(1):110-8. doi: 10.1016/j.gene.2013.09.115. Epub 2013 Oct 5.

197) Metabolite profiles of polyhydroxyalkanoate-producing Ralstonia eutropha H16
Toshiaki Fukui, Kenta Chou, Kazuo Harada, Izumi Orita, Yasumune Nakayama, Takeshi Bamba, Satoshi Nakamura, Eiichiro Fukusaki
Metabolomics (2014), vol10, issue2, pp. 190-201, doi:10.1007/s11306-013-0567-0 

196) Different-batch metabolome analysis of Saccharomyces cerevisiae based on gas chromatography/mass spectrometry.
Kawase N, Tsugawa H, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Feb;117(2):248-55. doi: 10.1016/j.jbiosc.2013.07.008. Epub 2013 Aug 19.

195) Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
Zaitsu K, Miyawaki I, Bando K, Horie H, Shima N, Katagi M, Tatsuno M, Bamba T, Sato T, Ishii A, Tsuchihashi H, Suzuki K, Fukusaki E.
Anal Bioanal Chem. 2014 Feb;406(5):1339-54. doi: 10.1007/s00216-013-7234-1. Epub 2013 Aug 4.

194) Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry.
Tsugawa H, Tsujimoto Y, Sugitate K, Sakui N, Nishiumi S, Bamba T, Fukusaki E.
J Biosci Bioeng. 2014 Jan;117(1):122-8. doi: 10.1016/j.jbiosc.2013.06.009. Epub 2013 Jul 16.


193) Ketoacyl synthase domain is a major determinant for fatty acyl chain length in Saccharomyces cerevisiae.
Sangwallek J, Kaneko Y, Sugiyama M, Ono H, Bamba T, Fukusaki E, Harashima S.
Arch Microbiol. 2013 Dec;195(12):843-52. doi: 10.1007/s00203-013-0933-3. Epub 2013 Nov 8.

192) Monitoring the ripening process of Cheddar cheese based on hydrophilic component profiling using gas chromatography-mass spectrometry.
Ochi H, Sakai Y, Koishihara H, Abe F, Bamba T, Fukusaki E.
J Dairy Sci. 2013 Dec;96(12):7427-41. doi: 10.3168/jds.2013-6897. Epub 2013 Oct 17.

191) SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.
Ulanova D, Kitani S, Fukusaki E, Nihira T.
Appl Environ Microbiol. 2013 Dec;79(24):7916-21. doi: 10.1128/AEM.02843-13. Epub 2013 Oct 11.

190)  Fixation of CO2 in Clostridium cellulovorans analyzed by 13C-isotopomer-based target metabolomics.
Shinohara M, Sakuragi H, Morisaka H, Miyake H, Tamaru Y, Fukusaki E, Kuroda K, Ueda M.
AMB Express. 2013 Oct 9;3(1):61. doi: 10.1186/2191-0855-3-61.

189) Investigation of β-Cryptoxanthin Fatty Acid Ester Compositions in Citrus Fruits Cultivated in Japan
Yusuke Wada, Atsuki Matsubara, Takato Uchikata, Yugo Iwasaki, Satoshi Morimoto, Katsuta Kan, Tetsuya Ookura, Eiichiro Fukusaki, Takeshi Bamba
Food and Nutrition 4, 98-104 (2013) 

Matsuda F, Tsugawa H, Fukusaki E.
Anal Chem. 2013 Sep 3;85(17):8291-7. doi: 10.1021/ac401564v. Epub 2013 Aug 14.

187) Selection of Discriminant Marker for Authentication of Asian Palm Civet Coffee (Kopi Luwak): A Metabolomics Approach.
Jumhawan U, Putri SP, Yusianto Y, Marwanni E, Bamba T, Fukusaki E.
J Agric Food Chem. 2013 Aug 21;61(33):7994-8001. doi: 10.1021/jf401819s. Epub 2013 Aug 12.

Metabolic Profiling of Oxidized Lipid-Derived Volatiles in Blood by Gas Chromatography/Mass Spectrometry with In-Tube Extraction
Shoji Kakuta, Yasuhiko Bando, Shin Nishiumi, Masaru Yoshida, Eiichiro Fukusaki, Takeshi Bamba
Mass Spectroometry Vol. 2 (2013) No. 1. doi: DOI: 10.5702/massspectrometry.A0018. Epub 2013 April 26

185) Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis.
Nirala NK, Rahman M, Walls SM, Singh A, Zhu LJ, Bamba T, Fukusaki E, Srideshikan SM, Harris GL, Ip YT, Bodmer R, Acharya UR.
PLoS Genet. 2013 Jun;9(6):e1003556. doi: 10.1371/journal.pgen.1003556. Epub 2013 Jun 20.

184) Supercritical fluid chromatography/Orbitrap mass spectrometry based lipidomics platform coupled with automated lipid identification software for accurate lipid profiling.
Yamada T, Uchikata T, Sakamoto S, Yokoi Y, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.
J Chromatogr A. 2013 Aug 2;1301:237-42. doi: 10.1016/j.chroma.2013.05.057. Epub 2013 Jun 1.

Development of a practical metabolite identification technique for non-targeted metabolomics.
Ogura T, Bamba T, Fukusaki E.
J Chromatogr A. 2
013 Aug 2;1301:73-9. doi: 10.1016/j.chroma.2013.05.054. Epub 2013 May 29.

Inflammation and Resolution Are Associated with Upregulation of Fatty Acid β-Oxidation in Zymosan-Induced Peritonitis.
Fujieda Y, Manno A, Hayashi Y, Rhodes N, Guo L, Arita M, Bamba T, Fukusaki E.
PLoS One. 2013 Jun 11;8(6):e66270. doi: 10.1371/journal.pone.0066270. Print 2013.

181) Simultaneous and rapid analysis of bile acids including conjugates by supercritical fluid chromatography coupled to tandem mass spectrometry.
Taguchi K, Fukusaki E, Bamba T.
J Chromatogr A. 2013 May 28. doi:pii: S0021-9673(13)00811-X. 10.1016/j.chroma.2013.05.043. [Epub ahead of print]

Acquisition of thermotolerant yeast Saccharomyces cerevisiae by breeding via stepwise adaptation.
Satomura A, Katsuyama Y, Miura N, Kuroda K, Tomio A, Bamba T, Fukusaki E, Ueda M.
Biotechnol Prog. 2013 May 16. doi: 10.1021/btpr.1754. [Epub ahead of print]

179) MRMPROBS: Data Assessment and Metabolite Identification Tool for Large-scale MRM-based Widely Targeted Metabolomics.
Tsugawa H, Arita M, Kanazawa M, Ogiwara A, Bamba T, Fukusaki E.
Anal Chem. 2013 May 21;85(10):5191-9. doi: 10.1021/ac400515s. Epub 2013 May 1.

Development of a lipid profiling system using reverse-phase liquid chromatography coupled to high-resolution mass spectrometry with rapid polarity switching and an automated lipid identification software.
Yamada T, Uchikata T, Sakamoto S, Yokoi Y, Fukusaki E, Bamba T.
J Chromatogr A. 2013 Jan 25. doi:pii: S0021-9673(13)00185-4. 10.1016/j.chroma.2013.01.078. [Epub ahead of print]
Simultaneous profiling of polar lipids by supercritical fluid chromatography/tandem mass spectrometry with methylation.
Lee JW, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.
J Chromatogr A. 2013 Mar 1;1279:98-107. doi: 10.1016/j.chroma.2013.01.020. Epub 2013 Jan 10.

Application of ion mobility-mass spectrometry to microRNA analysis.
Takebayashi K, Hirose K, Izumi Y, Bamba T, Fukusaki E.
J Biosci Bioeng. 2013 Mar;115(3):332-8. doi: 10.1016/j.jbiosc.2012.10.006. Epub 2012 Nov 30.

Vascular plant one-zinc finger protein 1/2 transcription factors regulate abiotic and biotic stress responses in Arabidopsis.
Nakai Y, Nakahira Y, Sumida H, Takebayashi K, Nagasawa Y, Yamasaki K, Akiyama M, Ohme-Takagi M, Fujiwara S, Shiina T, Mitsuda N, Fukusaki E, Kubo Y, Sato MH.
Plant J. 2013 Mar;73(5):761-75. doi: 10.1111/tpj.12069. Epub 2013 Feb 12.

Effect of gallic acid on peptides released by trypsin digestion of bovine α-casein.
Lai P, Okazawa A, Izumi Y, Bamba T, Fukusaki E, Yoshikawa M, Kobayashi A.
J Biosci Bioeng. 2013 Mar;115(3):259-67. doi: 10.1016/j.jbiosc.2012.10.003. Epub 2012 Nov 17.


173) High-throughput simultaneous analysis of pesticides by supercritical fluid chromatography/tandem mass spectrometry.
Ishibashi M, Ando T, Sakai M, Matsubara A, Uchikata T, Fukusaki E, Bamba T.
J Chromatogr A. 2012 Nov 30;1266:143-8. doi: 10.1016/j.chroma.2012.09.067. Epub 2012 Sep 28.
PMID: 23102524 [PubMed - as supplied by publisher]

172) Metabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in rats.
Fujieda Y, Ueno S, Ogino R, Kuroda M, Jönsson TJ, Guo L, Bamba T, Fukusaki E.
PLoS One. 2012;7(8):e43152. Epub 2012 Aug 13.
PMID: 22912814 [PubMed - in process]

171) Metabolic fingerprinting of hard and semi-hard natural cheeses using gas chromatography with flame ionization detector for practical sensory prediction modeling.
Ochi H, Bamba T, Naito H, Iwatsuki K, Fukusaki E.
J Biosci Bioeng. 2012 Nov;114(5):506-11. doi: 10.1016/j.jbiosc.2012.06.002. Epub 2012 Jul 21.
PMID: 22824260 [PubMed - as supplied by publisher]

170) High-throughput and sensitive analysis of 3-monochloropropane-1,2-diol fatty acid esters in edible oils by supercritical fluid chromatography/tandem mass spectrometry.
Hori K, Matsubara A, Uchikata T, Tsumura K, Fukusaki E, Bamba T.
J Chromatogr A. 2012 Aug 10;1250:99-104. doi: 10.1016/j.chroma.2012.06.017. Epub 2012 Jun 15.
PMID: 22749582 [PubMed - in process]

169) High-throughput phospholipid profiling system based on supercritical fluid extraction-supercritical fluid chromatography/mass spectrometry for dried plasma spot analysis.
Uchikata T, Matsubara A, Fukusaki E, Bamba T.
J Chromatogr A. 2012 Aug 10;1250:69-75. Epub 2012 Jun 17.
PMID: 22749580 [PubMed - in process]

168) Chloroplast-mediated activation of plant immune signalling in Arabidopsis.
Nomura H, Komori T, Uemura S, Kanda Y, Shimotani K, Nakai K, Furuichi T, Takebayashi K, Sugimoto T, Sano S, Suwastika IN, Fukusaki E, Yoshioka H, Nakahira Y, Shiina T.
Nat Commun. 2012 Jun 26;3:926. doi: 10.1038/ncomms1926.
PMID: 22735454 [PubMed - in process]

167) Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver.
Suzuki N, Uefuji H, Nishikawa T, Mukai Y, Yamashita A, Hattori M, Ogasawara N, Bamba T, Fukusaki EI, Kobayashi A, Ogata Y, Sakurai N, Suzuki H, Shibata D, Nakazawa Y.
Planta. 2012 Nov;236(5):1405-17. doi: 10.1007/s00425-012-1679-x. Epub 2012 Jun 24.
PMID: 22729820 [PubMed - as supplied by publisher]

166) Development of oxidized phosphatidylcholine isomer profiling method using supercritical fluid chromatography/tandem mass spectrometry.
Uchikata T, Matsubara A, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.
J Chromatogr A. 2012 Aug 10;1250:205-11. doi: 10.1016/j.chroma.2012.05.083. Epub 2012 May 30.
PMID: 22717033 [PubMed - as supplied by publisher]

165) High-accuracy analysis system for the redox status of coenzyme Q(10) by online supercritical fluid extraction-supercritical fluid chromatography/mass spectrometry.
Matsubara A, Harada K, Hirata K, Fukusaki E, Bamba T.
J Chromatogr A. 2012 Aug 10;1250:76-9. Epub 2012 May 9.
PMID: 22673808 [PubMed - in process]

164) Identification of Biomarkers of Stent Restenosis With Serum Metabolomic Profiling Using Gas Chromatography/Mass Spectrometry.
Hasokawa M, Shinohara M, Tsugawa H, Bamba T, Fukusaki E, Nishiumi S, Nishimura K, Yoshida M, Ishida T, Hirata Circ J. 2012;76(8):1864-73. Epub 2012 May 16. 

163) Gallic acid oxidizes Met residues in peptides released from bovine β-lactoglobulin by in vitro digestion.
Lai P, Okazawa A, Izumi Y, Bamba T, Fukusaki E, Yoshikawa M, Kobayashi A.
J Biosci Bioeng. 2012 Sep;114(3):297-305. Epub 2012 May 30.

162) Gas chromatography-mass spectrometry based metabolic profiling for the identification of discrimination markers of Angelicae Radix and its application to gas chromatography-flame ionization detector system.
Kobayashi S, Putri SP, Yamamoto Y, Donghyo K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2012 Aug;114(2):232-6. Epub 2012 May 25.
PMID: 22633242 [PubMed - in process]

161) Metabolic profiling and identification of the genetic varieties and agricultural origin of Cnidium officinale and Ligusticum chuanxiong.
Kobayashi S, Nagasawa S, Yamamoto Y, Donghyo K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2012 Jul;114(1):86-91. Epub 2012 May 22.
PMID: 22627050 [PubMed - in process]

160) Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis.
Yamamoto S, Bamba T, Sano A, Kodama Y, Imamura M, Obata A, Fukusaki E.
J Biosci Bioeng. 2012 Aug;114(2):170-5. Epub 2012 May 19.
PMID: 22608993 [PubMed - in process]

159) Metabolomics-based component profiling of hard and semi-hard natural cheeses with gas chromatography/time-of-flight-mass spectrometry, and its application to sensory predictive modeling.
Ochi H, Naito H, Iwatsuki K, Bamba T, Fukusaki E.
J Biosci Bioeng. 2012 Jun;113(6):751-8. Epub 2012 Mar 2.
PMID: 22386562 [PubMed - as supplied by publisher]

158) Highly sensitive and rapid profiling method for carotenoids and their epoxidized products using supercritical fluid chromatography coupled with electrospray ionization- triple quadrupole mass spectrometry.
Matsubara A, Uchikata T, Shinohara M, Nishiumi S, Yoshida M, Fukusaki E, Bamba T.
J Biosci Bioeng. 2012 Jun;113(6):782-7. Epub 2012 Feb 29.PMID: 22382010 [PubMed - as supplied by publisher]

157) Application of electrospray ionization ion trap/time-of-flight mass spectrometry for chemically-synthesized small RNAs.
Izumi Y, Takimura S, Yamaguchi S, Iida J, Bamba T, Fukusaki E.
J Biosci Bioeng. 2012 Mar;113(3):412-9. Epub 2011 Dec 5.PMID: 22153845 [PubMed - as supplied by publisher]

156) Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer.
Ikeda A, Nishiumi S, Shinohara M, Yoshie T, Hatano N, Okuno T, Bamba T, Fukusaki E, Takenawa T, Azuma T, Yoshida M.
Biomed Chromatogr. 2012 May;26(5):548-58. doi: 10.1002/bmc.1671. Epub 2011 Jul 20.


155) Development of a polar lipid profiling method by supercritical fluid chromatography/mass spectrometry.

Lee JW, Yamamoto T, Uchikata T, Matsubara A, Fukusaki E, Bamba T.

J Sep Sci. 2011 Dec;34(24):3553-60. doi: 10.1002/jssc.201100539.

[PubMed - in process]

154) Use of ultra-performance liquid chromatography/time-of-flight mass spectrometry with nozzle-skimmer fragmentation for comprehensive quantitative analysis of secondary metabolites in Arabidopsis thaliana.

Sugimoto T, Bamba T, Izumi Y, Nomura H, Shiina T, Fukusaki E.

J Sep Sci. 2011 Dec;34(24):3587-96. doi: 10.1002/jssc.201100552. Epub 2011 Nov 21.

[PubMed - in process]

153) Application of supercritical fluid chromatography/mass spectrometry to lipid profiling of soybean.

Lee JW, Uchikata T, Matsubara A, Nakamura T, Fukusaki E, Bamba T.

J Biosci Bioeng. 2012 Feb;113(2):262-8. Epub 2011 Nov 21.

[PubMed - in process]

Wada Y, Matsubara A, Uchikata T, Iwasaki Y, Morimoto S, Kan K, Okura T, Fukusaki E, Bamba T.

J Sep Sci. 2011 Dec;34(24):3546-52. doi: 10.1002/jssc.201100376. Epub 2011 Oct 31.

[PubMed - in process]

151) Simultaneous quantification of lignans in Arabidopsis thaliana by highly sensitive capillary liquid chromatography-electrospray ionization-ion trap mass spectrometry.
Atsushi Okazawa, Katsuhito Hori, Ryohei Okumura, Yoshihiro Izumi, Naoki Hata, TakeshiBamba, Eiichiro Fukusaki, Eiichiro Ono, Honoo Satake and Akio Kobayashi
Plant Biotechnology, Vol. 28 (2011) , No. 3 pp.287-293

149) Influences of methamphetamine-induced acute intoxication on urinary and plasma metabolic profiles in the rat.
Shima N, Miyawaki I, Bando K, Horie H, Zaitsu K, Katagi M, Bamba T, Tsuchihashi H, Fukusaki E. 
Toxicology. 2011 Sep 5;287(1-3):29-37. Epub 2011 May 27.

148) Practical non-targeted gas chromatography/mass spectrometry-based metabolomics platform for metabolic phenotype analysis. 
Tsugawa H, Bamba T, Shinohara M, Nishiumi S, Yoshida M, Fukusaki E. 
J Biosci Bioeng. 2011 Sep;112(3):292-8. Epub 2011 Jun 8.

J Biosci Bioeng. 2011 Sep;112(3):247-51. Epub 2011 Jun 2.

146) Single-embryo metabolomics and systematic prediction of developmental stage in zebrafish.

Hayashi S, Yoshida M, Fujiwara T, Maegawa S, Fukusaki E.

Z Naturforsch C. 2011 Mar-Apr;66(3-4):191-8.

Tsugawa H, Tsujimoto Y, Arita M, Bamba T, Fukusaki E.
BMC Bioinformatics. 2011 May 4;12:131.

144) A metabolomic approach to lung cancer.
Hori S, Nishiumi S, Kobayashi K, Shinohara M, Hatakeyama Y, Kotani Y, Hatano N, Maniwa Y, Nishio W, Bamba T, Fukusaki E, Azuma T, Takenawa T, Nishimura Y, Yoshida M.
Lung Cancer. 2011 Nov;74(2):284-92. Epub 2011 Mar 15.

143) GABA metabolism pathway genes, UGA1 and GAD1, regulate replicative lifespan in Saccharomyces cerevisiae.
Kamei Y, Tamura T, Yoshida R, Ohta S, Fukusaki E, Mukai Y.
Biochem Biophys Res Commun. 2011 Apr 1;407(1):185-90. Epub 2011 Mar 1.

142) Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors.
Yonamine I, Bamba T, Nirala NK, Jesmin N, Kosakowska-Cholody T, Nagashima K, Fukusaki E, Acharya JK, Acharya U.
J Cell Biol. 2011 Feb 21;192(4):557-67. Epub 2011 Feb 14.
PMID: 21321100 [PubMed - indexed for MEDLINE]

141) GC-MS-based metabolomics reveals mechanism of action for hydrazine induced hepatotoxicity in rats.
Bando K, Kunimatsu T, Sakai J, Kimura J, Funabashi H, Seki T, Bamba T, Fukusaki E.
J Appl Toxicol,.2011. 31(6): 524-535. Epub Date 2010/12/15 
PMID: 21154879 [PubMed - as supplied by publisher]

140) Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids.
Daikoku S, Ono Y, Ohtake A, Hasegawa Y, Fukusaki E, Suzuki K, Ito Y, Goto S, Kanie O.
Analyst. 2011 Mar 7;136(5):1046-50. Epub 2010 Dec 20.
PMID: 21173959 [PubMed - indexed for MEDLINE]

139) CDase is a pan-ceramidase in Drosophila.
Yuan C, Rao RP, Jesmin N, Bamba T, Nagashima K, Pascual A, Preat T, Fukusaki E, Acharya U, Acharya JK.
Mol Biol Cell. 2011 Jan 1;22(1):33-43. Epub 2010 Dec 9.
PMID: 21148295 [PubMed - indexed for MEDLINE] 


138) Nishiumi, S., M. Shinohara, A. Ikeda, T. Yoshie, N. Hatano, S. Kakuyama, S. Mizuno, T. Sanuki, H. Kutsumi, E. Fukusaki, T. Azuma, T. Takenawa, and M. Yoshida, Serum metabolomics as a novel diagnostic approach for pancreatic cancer. Metabolomics, 2010. 6(4): p. 518-528.  [DOI]


137) Bamba T, Murayoshi M, Gyoksen K, Nakazawa Y, Okumoto H, Katto H, Fukusaki E, Kobayashi A. " Contribution of mevalonate and methylerythritol phosphate pathways to polyisoprenoid biosynthesis in the rubber-producing plantEucommia ulmoides oliver."  Z Naturforsch C. 2010 May-Jun;65(5-6):363-72.  [Pub Med]

136) Bando, K., R. Kawahara, T. Kunimatsu, J. Sakai, J. Kimura, H. Funabashi, T. Seki, T. Bamba and E. Fukusaki. "Influences of biofluid sample collection and handling procedures on GC-MS based metabolomic studies." J Biosci Bioeng110(4): p. 491-499. Epub date 2010/06/17  [Pub Med]


135) Yoshida, R., T. Tamura, C. Takaoka, K. Harada, A. Kobayashi, Y. Mukai and E. Fukusaki. "Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of aging-related mutants." Aging Cell. 2010 Aug;9(4):616-25. Epub 2010 Jun 9.  [Pub Med]


134) Ishikawa, K., Yoshimura, K., Harada, K., Fukusaki, E., Ogawa, T., Tamoi, M. and Shigeoka, S. "AtNUDX6, an ADP-ribose/NADH pyrophosphohydrolase in Arabidopsis, positively regulates NPR1-dependent salicylic acid signaling." Plant Physiol. 154(4): 2000-2012 (2010)   Epub 2010/02/24  [Pub Med]


133) Tianniam, S., Bamba, T. and Fukusaki, E. "Pyrolysis GC-MS-based metabolite fingerprinting for quality evaluation of commercial Angelica acutiloba roots." J Biosci Bioeng 109(1): 89-93 (2010)  Epub date 2009/07/23  [Pub Med]


132) Hasunuma, T., Harada, K., Miyazawa, S., Kondo, A., Fukusaki, E. and Miyake, C. "Metabolic turnover analysis by a combination of in vivo 13C-labelling from 13CO2 and metabolic profiling with CE-MS/MS reveals rate-limiting steps of the C3 photosynthetic pathway in Nicotiana tabacum leaves." J Exp Bot 61(4): 1041-1051.(2010)  Epub date 2009/12/21 [Pub Med]


131) Takeno, S., Bamba, T., Nakazawa, Y., Fukusaki, E., Okazawa, A. and Kobayashi, A. "High-Throughput and Highly Sensitive Analysis Method for Polyisoprene in Plants by Pyrolysis-Gas Chromatography/Mass Spectrometry." Biosci Biotechnol Biochem. 74(1): 13-17 (2010).  Epub date 2010/01/07  [Pub Med]






130) Ikeda, T., Altaf-Ul-Amin, M., Takabayashi, H. and Fukusaki, E. "DrEFTIR: The data mining software for fourier transform near-infrared reflectance spectroscopy focused on food metabolic finger printing." Plant Biotechnology 26(5): 451-457.(2009)  [J-stage]


129) Dasgupta, U., Bamba, T., Chiantia, S., Karim, P., Abou Tayoun, A. N., Yonamine, I., Rawat, S. S., Rao, R. P., Nagashima, K., Fukusaki, E., Puri, V., Dolph, P. J., Schwille, P., Acharya, J. K. and Acharya, U. "Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction." Proc Natl Acad Sci U S A.106(47): 20063-20068 (2009)  Epub date 2009/11/05  [Pub Med]


128) Yamamoto, H., Yamaji, H., Abe, Y., Harada, K., Waluyo, D., Fukusaki, E., Kondo, A., Ohno, H. and Fukuda, H. "Dimensionality reduction for metabolome data using PCA, PLS, OPLS, and RFDA with differential penalties to latent variables." Chemometrics and Intelligent Laboratory Systems98. 136-142 (2009)  Epub date 2009/06/02  [Science Direct]


127) Ishikawa, K., Ogawa, T., Hirosue, E., Nakayama, Y., Harada, K., Fukusaki, E., Yoshimura, K. and Shigeoka, S. "Modulation of the poly(ADP-ribosyl)ation reaction via the Arabidopsis ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7, is involved in the response to oxidative stress." Plant Physiol151, 741-754 (2009)  Epub date 2009/08/05  [Pub Med]


126) Yamada, Y., Fukuda, W., Hirooka, K., Hiromoto, T., Nakayama, J., Imanaka, T., Fukusaki, E. and Fujiwara, S. "Efficient in vitro synthesis of cis-polyisoprenes using a thermostable cis-prenyltransferase from a hyperthermophilic archaeon Thermococcus kodakaraensis." J Biotechnol 143(2): 151-156.(2009) Epub date 2009/07/05 [Pub Med]


125Takagi, K., Okazawa, A., Wada, Y., Mongkolchaiyaphruek, A., Fukusaki, E., Yoneyama, K., Takeuchi, Y. and Kobayashi, A. "Unique phytochrome responses of the holoparasitic plant Orobanche minor." New Phytol 182(4): 965-974. (2009) Epub date 2009/03/20  [Pub Med]


124) Izumi, Y., Okazawa, A., Bamba, T., Kobayashi, A. and Fukusaki, E. "Development of a method for comprehensive and quantitative analysis of plant hormones by highly sensitive nanoflow liquid chromatography-electrospray ionization-ion trap mass spectrometry." Anal Chim Acta 648(2): 215-225.(2009)  Epub date 2009/07/04  [Pub Med]


123) Jumtee, K., Okazawa, A., Harada, K., Fukusaki, E., Takano, M. and Kobayashi, A. "Comprehensive metabolite profiling of phyA phyB phyC triple mutants to reveal their associated metabolic phenotype in rice leaves." J Biosci Bioeng108(2): 151-159.(2009)  [Pub Med]


122) Jumtee, K., Bamba, T. and Fukusaki, E. "Fast GC-FID based metabolic fingerprinting of Japanese green tea leaf for its quality ranking prediction." J Sep Sci 32(13): 2296-2304.(2009) Epub date 2009/06/30  [Pub Med]


121) Tianniam, S., Bamba, T. and Fukusaki, E. "Non-targeted metabolite fingerprinting of oriental folk medicine Angelica acutiloba roots by ultra performance liquid chromatography time-of-flight mass spectrometry." J Sep Sci 32(13): 2233-2244.(2009)  Epub date 2009/06/30  [Pub Med]


120) Hayashi, S., Akiyama, S., Tamaru, Y., Takeda, Y., Fujiwara, T., Inoue, K., Kobayashi, A., Maegawa, S. and Fukusaki, E. "A novel application of metabolomics in vertebrate development." Biochem Biophys Res Commun 386(1): 268-272.(2009) Epub date 2009/06/10  [Pub Med]


119) Sando, T., Hayashi, T., Takeda, T., Akiyama, Y., Nakazawa, Y., Fukusaki, E. and Kobayashi, A. "Histochemical study of detailed laticifer structure and rubber biosynthesis-related protein localization in Hevea brasiliensis using spectral confocal laser scanning microscopy." Planta230(1): 215-225. (2009)  Epub date 2009/05/05  [Pub Med]


118) Matsubara, A., Bamba, T., Ishida, H., Fukusaki, E. and Hirata, K. "Highly sensitive and accurate profiling of carotenoids by supercritical fluid chromatography coupled with mass spectrometry." J Sep Sci 32(9): 1459-1464.(2009) Epub date 2009/04/09  [Pub Med]


117) Oishi, T., Tanaka, K.-i., Hashimoto, T., Shinbo, Y., Jumtee, K., Bamba, T., Fukusaki, E., Suzuki, H., Shibata, D., Takahashi, H., Asahi, H., Kurokawa, K., Nakamura, Y., Hirai, A., Nakamura, K., Altaf-Ul-Amin, M. and Kanaya, S. "An approach to peak detection in GC-MS chromatograms and application of KNApSAcK database in prediction of candidate metabolites." Plant Biotechnology 26(1): 167-174.(2009)  [J-Stage]


116) Izumi, Y., Kajiyama, S., Nakamura, R., Ishihara, A., Okazawa, A., Fukusaki, E., Kanematsu, Y. and Kobayashi, A. "High-resolution spatial and temporal analysis of phytoalexin production in oats." Planta 229(4): 931-943.(2009) , Epubdate 2009 Jan 16.  [Pub Med]


115) Kim, J. H., Sunako, M., Ono, H., Murooka, Y., Fukusaki, E. and Yamashita, M. "Characterization of the C-terminal truncated form of amylopullulanase from Lactobacillus plantarum L137." J Biosci Bioeng 107(2): 124-129.(2009)  [Pub Med]


114) Igarashi, D., Izumi, Y., Dokiya, Y., Totsuka, K., Fukusaki, E. and Ohsumi, C. "Reproductive organs regulate leaf nitrogen metabolism mediated by cytokinin signal." Planta 229(3): 633-644.(2009) , Epub date 2008 Dec 2.  [Pub Med]


113) Ogawa, T., Ishikawa, K., Harada, K., Fukusaki, E., Yoshimura, K. and Shigeoka, S. "Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants." Plant J 57(2): 289-301.(2009) , Epub date 2008 Oct 14. [Pub Med]






112) Kawai, S., Phan, T. A., Kono, E., Harada, K., Okai, C., Fukusaki, E. and Murata, K. "Transcriptional and metabolic response in yeast Saccharomyces cerevisiae cells during polyethylene glycol-dependent transformation." J Basic Microbiol 49(1): 73-81.(2008) , Epub date 2008 Sep 16  [Pub Med]


111) Takeno, S., Bamba, T., Nakazawa, Y., Fukusaki, E., Okazawa, A. and Kobayashi, A. "A high-throughput and solvent-free method for measurement of natural polyisoprene content in leaves by Fourier transform near infrared spectroscopy." J Biosci Bioeng 106(6): 537-540.(2008)  [PubMed]


110) Kim, J. H., Sunako, M., Ono, H., Murooka, Y., Fukusaki, E. and Yamashita, M.  "Characterization of Gene Encoding Amylopullulanase from Plant-Originated Lactic Acid Bacterium, Lactobacillus plantarum L137." J Biosci Bioeng 106(5): 449-459.(2008)  [Pub Med]


109) Sando, T., Takeno, S., Watanabe, N., Okumoto, H., Kuzuyama, T., Yamashita, A., Hattori, M., Ogasawara, N., Fukusaki, E. and Kobayashi, A. "Cloning and Characterization of the 2-C-Methyl-D-erythritol 4-Phosphate (MEP) Pathway Genes of a Natural-Rubber Producing Plant, Hevea brasiliensis." Biosci Biotechnol Biochem72(11), 2903-2917 (2008) [Pub Med]


108) Pongsuwan, W., Bamba, T., Harada, K., Yonetani, T., Kobayashi, A. and Fukusaki, E. "High-Throughput Technique for Comprehensive Analysis of Japanese Green Tea Quality Assessment Using Ultra-performance Liquid Chromatography with Time-of-Flight Mass Spectrometry (UPLC/TOF MS)."  J Agric Food Chem 56(22): 10705-10708.(2008)  [Pub Med]


107) Kajiyama, S., Joseph, B., Inoue, F., Shimamura, M., Fukusaki, E., Tomizawa, K. and Kobayashi, A. "Transient gene expression in guard cell chloroplasts of tobacco using ArF excimer laser microablation." J Biosci Bioeng 106(2): 194-198.(2008)  [Pub Med]


106) Sando, T., Takaoka, C., Mukai, Y., Yamashita, A., Hattori, M., Ogasawara, N., Fukusaki, E. and Kobayashi, A. "Cloning and Characterization of Mevalonate Pathway Genes in a Natural Rubber Producing Plant, Hevea brasiliensis."Biosci Biotechnol Biochem.72(8): 2049-2060 (2008) [Pub Med]


105) Tarachiwin, L., Katoh, A., Ute, K. and Fukusaki, E. "Quality evaluation of Angelica acutiloba Kitagawa roots by (1)H NMR-based metabolic fingerprinting." J Pharm Biomed Anal. 48(1): 42-48 (2008)  [Pub Med]


104) Tianniam, S., Tarachiwin, L., Bamba, T., Kobayashi, A. and Fukusaki, E. "Metabolic profiling of Angelica acutilobaroots utilizing gas chromatography-time-of-flight-mass spectrometry for quality assessment based on cultivation area and cultivar via multivariate pattern recognition." J Biosci Bioeng 105(6): 655-659.(2008) [Pub Med]


103) Tarachiwin, L., Masako, O. and Fukusaki, E. "Quality evaluation and prediction of Citrullus lanatus by 1H NMR-based metabolomics and multivariate analysis." J Agric Food Chem 56(14): 5827-5835.(2008) [Pub Med]


102) Okajima, M. K., Bamba, T., Kaneso, Y., Hirata, K., Fukusaki, E., Kajiyama, S. i. and Kaneko, T. "Supergiant Ampholytic Sugar Chains with Iimbalanced Charge Ratio from Saline Ultra-absorbent Hydrogels." Macromolecules 41(12): 4061-4064.(2008) [ACS Publications]


101) Bamba, T., Shimonishi, N., Matsubara, A., Hirata, K., Nakazawa, Y., Kobayashi, A. and Fukusaki, E. "High throughput and exhaustive analysis of diverse lipids by using supercritical fluid chromatography-mass spectrometry for metabolomics." J Biosci Bioeng 105(5): 460-469.(2008) [Pub Med]


100) Hasunuma, T., Takeno, S., Hayashi, S., Sendai, M., Bamba, T., Yoshimura, S., Tomizawa, K., Fukusaki, E. and Miyake, C. "Overexpression of 1-Deoxy-d-xylulose-5-phosphate reductoisomerase gene in chloroplast contributes to increment of isoprenoid production." J Biosci Bioeng 105(5): 518-526.(2008) [Pub Med]


99) Yamamoto, H., Yamaji, H., Fukusaki, E., Ohno, H. and Fukuda, H. "Canonical correlation analysis for multivariate regression and its application to metabolic fingerprinting." Biochemical Engineering Journal 40(2): 199-204.(2008)[Science Direct]


98) Takeno, S., Bamba, T., Nakazawa, Y., Fukusaki, E., Okazawa, A. and Kobayashi, A. "Quantification of trans-1,4-polyisoprene in Eucommia ulmoides by fourier transform infrared spectroscopy and pyrolysis-gas chromatography/mass spectrometry." J Biosci Bioeng 105(4): 355-359.(2008) [Pub Med]


97) Ikeda, T., Altaf-Ul-Amin, M., Prvin, A. K., Kanaya, S., Yonetani, T. and Fukusaki, E. "Predicting Rank of Japanese Green Teas by Derivative Profiles of Spectra Obtained from Fourier Transform Near-Infrared Reflectance Spectroscopy."Journal of Computer Aided Chemistry 9: 37-46.(2008) [J-Stage]


96) Jumtee, K., Bamba, T., Okazawa, A., Fukusaki, E. and Kobayashi, A. "Integrated metabolite and gene expression profiling revealing phytochrome A regulation of polyamine biosynthesis of Arabidopsis thaliana." J Exp Bot. 59 (6): 1187-1200 (2008) [Pub Med]


95) Harada, K., Ohyama, Y., Tabushi, T., Kobayashi, A. and Fukusaki, E. "Quantitative analysis of anionic metabolites forCatharanthus roseus by capillary electrophoresis using sulfonated capillary coupled with electrospray ionization-tandem mass spectrometry." J Biosci Bioeng 105(3): 249-260.(2008) [Pub Med]


94) Pongsuwan, W., Bamba, T., Yonetani, T., Kobayashi, A. and Fukusaki, E. "Quality Prediction of Japanese Green Tea Using Pyrolyzer Coupled GC/MS Based Metabolic Fingerprinting." J Agric Food Chem. 56(3): 744-750 (2008) [Pub Med]


93) Fujiwara, S., Yamanaka, A., Yamada, Y., Hirooka, K., Higashibata, H., Fukuda, W., Nakayama, J., Imanaka, T. and Fukusaki, E. "Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system." Biochem Biophys Res Commun 365(1): 118-123.(2008) [Pub Med]


92) Prasitchoke, P., Kaneko, Y., Bamba, T., Fukusaki, E., Kobayashi, A. and Harashima, S. "The essential fatty acid myristate causes severe growth retardation in Hpelo disruptants of the yeast Hansenula polymorpha." Arch Microbiol189(4): 297-304.(2008) [Pub Med]





91) Ikeda, T., Kanaya, S., Yonetani, T., Kobayashi, A. and Fukusaki, E. "Prediction of Japanese green tea ranking by fourier transform near-infrared reflectance spectroscopy." J Agric Food Chem 55(24): 9908-9912.(2007) [Pub Med]


90) Tarachiwin, L., Ute, K., Kobayashi, A. and Fukusaki, E. "(1)H NMR based metabolic profiling in the evaluation of Japanese green tea quality." J Agric Food Chem 55(23): 9330-9336.(2007) [Pub Med]


89) Kajiyama, S., Inoue, F., Yoshikawa, Y., Shoji, T., Fukusaki, E. and Kobayashi, A. "Novel plant transformation system by gene-coated gold particle introduction into specific cell using ArF excimer laser." Plant Biotechnology 24: 315-320.(2007) [Plant Biotech]


88) Sakakura, M., Kajiyama, S., Tsutsumi, M., Si, J., Fukusaki, E., Tamaru, Y., Akiyama, S., Miura, K., Hirao, K. and Ueda, M. "Femtosecond Pulsed Laser as a Microscalpel for Microdissection and Isolation of Specific Sections from Biological Samples." Jpn. J. Appl. Phys. 46(9A): 5859-5864.(2007) [JJAP]


87) Kim, J. K., Cho, M. R., Baek, H. J., Ryu, T. H., Yu, c. Y., Kim, M. J., Fukusaki, E. and Kobayashi, A. "Analysis of Metabolite Profile Data Using Batch-Learning Self-Organizing Maps." Journal of Plant Biology 50(4): 517-521.(2007)


86) Bamba, T., Sando, T., Miyabashira, A., Gyokusen, K., Nakazawa, Y., Su, Y., Fukusaki, E. and Kobayashi, A. "Periploca sepium Bunge as a model plant for rubber biosynthesis study." Z Naturforsch [C] 62(7-8): 579-582.(2007) [Pub Med]


85) Prasitchoke, P., Kaneko, Y., Sugiyama, M., Bamba, T., Fukusaki, E., Kobayashi, A. and Harashima, S. "Functional analysis of very long-chain fatty acid elongase gene, HpELO2, in the methylotrophic yeast Hansenula polymorpha." Appl Microbiol Biotechnol 76(2): 417-427.(2007) [Pub Med]


84) Prasitchoke, P., Kaneko, Y., Bamba, T., Fukusaki, E., Kobayashi, A. and Harashima, S. "Identification and characterization of a very long-chain fatty acid elongase gene in the methylotrophic yeast, Hansenula polymorpha." Gene391(1-2): 16-25.(2007) [Pub Med]


83) Kim, J. K., Bamba, T., Harada, K., Fukusaki, E. and Kobayashi, A. "Time-course metabolic profiling in Arabidopsis thaliana cell cultures after salt stress treatment." J Exp Bot 58(3): 415-424.(2007) [Pub Med]


82) Pongsuwan, W., Fukusaki, E., Bamba, T., Yonetani, T., Yamahara, T. and Kobayashi, A. "Prediction of Japanese green tea ranking by gas chromatography/mass spectrometry-based hydrophilic metabolite fingerprinting." J Agric Food Chem 55(2): 231-236.(2007) [Pub Med]





81) Kajiyama, S., Harada, K., Fukusaki, E. and Kobayashi, A. "Single cell-based analysis of Torenia petal pigments by a combination of ArF excimer laser microsampling and nano HPLC mass spectrometry." J Biosci Bioeng. 102(6): 575-578.(2006) [Pub Med]


80) Ohnishi, N., Furukawa, H., Hideyuki, H., Wang, J.-M., An, C.-I., Fukusaki, E., Kataoka, K., Ueno, K. and Kondo, A. "High-Efficiency Bioaffinity Separation of Cells and Proteins Using

Novel Thermoresponsive Biotinylated Magnetic Nanoparticles." NanoBiotechnology 2(1-2): 43-49.(2006) [Springer Link]


79) Ute, K., Yoshida, S., Kitayama, T., Bamba, T., Harada, K., Fukusaki, E., Kobayashi, A., Ishizuka, N., Minakuchi, H. and Nakanishi, K. "Size Exclusion Chromatography of Standard Polystyrenes with a Wide Range of Molecular Weight Up to 7.45 106 on Monolithic Silica Capillary columns." Polymer Journal 38(11): 1194-1197.(2006) [J-Stage]


78) Harada, K., Fukusaki, E., Bamba, T., Sato, F. and Kobayashi, A. "In vivo (15)n-enrichment of metabolites in suspension cultured cells and its application to metabolomics." Biotechnol Prog 22(4): 1003-1011.(2006) [Pub Med]


77) Harada, K., E. Fukusaki, and A. Kobayashi, "Pressure-Assisted Capillary Electrophoresis Mass Spectrometry using a Combination of Polarity Reversion and Electroosmotic Flow for the Metabolomics Anion Analysis." J. Biosci. Bioeng.:101(5): 403-409.(2006) [Pub Med]


76) Fukusaki, E., K. Jumtee, T. Bamba, T. Yamaji, and A. Kobayashi, "Metabolic fingerprinting and profiling of Arabidopsis thaliana leaf and its cultured cells T87 by GC/MS." Z Naturforsch [C]61(3-4): 267-72.(2006) [Pub Med]


75) Okazawa, A., L. Tango, Y. Itoh, E. Fukusaki, and A. Kobayashi, "Characterization and subcellular localization of chlorophyllase from Ginkgo biloba." Z Naturforsch [C]61(1-2): 111-7.(2006) [Pub Med]


74) Tabata, A., F. Namba, M. Yamada, T. Hasegawa, K. Nakahira, D. Hamada, H. Kitajima, E. Fukusaki, and I. Yanagihara, "Expression and purification of recombinant human annexin A2 in Pichia pastoris and utility of expression product for detecting annexin A2 antibody." J Biosci Bioeng101(2): 190-197.(2006) [Pub Med]


73) Kajiyama, S., T. Shoji, S. Okuda, Y. Izumi, E. Fukusaki, and A. Kobayashi, "A novel microsurgery method for intact plant tissue at the single cell level using ArF excimer laser microprojection." Biotechnol Bioeng93(2): 325-31.(2006) [Pub Med]





72) Bamba, T., Fukusaki, E., Minakuchi, H., Nakazawa, Y., and Kobayashi, A.: Separation of polyprenol and dolichol by monolithic silica capillary column chromatography. J Lipid Res46, 2295-8(2005). [Pub Med]


71) Kim, J.K., K. Harada, T. Bamba, E. Fukusaki, and A. Kobayashi, "Stable isotope dilution-based accurate comparative quantification of nitrogen-containing metabolites in Arabidopsis thaliana T87 cells using in vivo 15N-isotope enrichment."Biosci Biotechnol Biochem69(7): 1331-40.(2005) [Pub Med]


70) Nakae, Y., E.i. Fukusaki, S.-i. Kajiyama, A. Kobayashi, and I. Sakata, "Syntheses and Screening Tests of New Chlorin Derivatives as Photosensitizer." Journal of Photochemistry and PhotoBiology A: Chemistry174(3): 187-193.(2005)[Science Direct]


69) Fukui, T., Shiraki, K., Hamada, D., Hara, K., Miyata, T., Fujiwara, S., Mayanagi, K., Yanagihara, K., Iida, T., Fukusaki, E., Imanaka, T., Honda, T., and Yanagihara, I.: Thermostable Direct Hemolysin of Vibrio parahaemolyticus is a Bacterial Reversible Amyloid Toxin., Biochemistry44, 9825-9832 (2005). [Pub Med]      


68) Tarachiwin, L., Sakdapipanich, J., Ute, K., Kitayama, T., Bamba, T., Fukusaki, E.-i., Kobayashi, A., and Tanaka, Y.: Structural Characterization of a-Terminal Group of Natural Rubber. 1. Decomposition of Branch-Points by Lipase and Phosphatase Treatments., Biomacromolecules6, 1851-1857 (2005). [Pub Med]


67) Okazawa, A., Trakulnaleamsai, C., Hiramatsu, H., Fukusaki, E., Yoneyama, K., Takeuchi, Y., and Kobayashi, A.:Cloning of a cryptochrome homologue from the holoparasitic plant Orobanche minor Sm. Plant Physiol Biochem43, 499-502(2005).           [Pub Med]


66) Siddiqui, M.A., A. Yamanaka, K. Hirooka, T. Bamaba, A. Kobayashi, T. Imanaka, E. Fukusaki, and S. Fujiwara, "Enzymatic and structural characterization of type II isopentenyl diphosphate isomerase from hyperthermophilic archaeonThermococcus kodakaraensis." Biochem Biophys Res Commun331(4): 1127-36.(2005)  [Pub Med]


65) Nakae, Y., E.i. Fukusaki, S.-i. Kajiyama, A. Kobayashi, and I. Sakata, "The Convenient Screening Method using Albumin for the Tumor Localizing Property of Ga-porphyr in Complexes." Journal of Photochemistry and PhotoBiology A: Chemistry172(1), 55-61.(2005)    [Science Direct]


64) Nakae, Y., E.i. Fukusaki, S.-i. Kajiyama, A. Kobayashi, and I. Sakata, "Convenient Screening Methods for the Photosensitivity." Journal of Photochemistry and PhotoBiology A: Chemistry171(1): 91-95.(2005)  [Science Direct]


63) Hirooka, K., Y. Izumi, C.I. An, Y. Nakazawa, E. Fukusaki, and A. Kobayashi, "Functional Analysis of Two Solanesyl Diphosphate Synthases from Arabidopsis thaliana." Biosci Biotechnol Biochem69(3): 592-601.(2005)  [Pub Med]


62) An, C.I., A. Sawada, Y. Kawaguchi, E. Fukusaki, and A. Kobayashi, "Transient RNAi Induction against Endogenous Genes in Arabidopsis Protoplasts Using in Vitro-Prepared Double-Stranded RNA." Biosci Biotechnol Biochem69(2): 415-8.(2005) [Pub Med]


61) Fukusaki, E.i., K. Harada, T. Bamba, and A. Kobayashi, "An isotope effect on the comparative quantification of flavonoids by means of methylation-based stable isotope dilution coupled with capillary liquid chromatograph/mass spectrometry." J. Biosci. Bioeng.99(1): 75-77.(2005) [Pub Med]


60) Dubouzet, J.G., T. Morishige, N. Fujii, C.I. An, E.I. Fukusaki, K. Ifuku, and F. Sato, "Transient RNA Silencing of Scoulerine 9-O-Methyltransferase Expression by Double Stranded RNA in Coptis japonica Protoplasts." Biosci Biotechnol Biochem69(1): 63-70.(2005) [Pub Med]


59) Trakulnaleamsai, C., Okazawa, A., An, C.I., Kajiyama, S., Fukusaki, E., Yoneyama, K., Takeuchi, Y., and Kobayashi, A.: Isolation and Characterization of a cDNA Encoding Phytochrome A in the Non-Photosynthetic Parasitic Plant, Orobanche minor Sm, Biosci Biotechnol Biochem69, 71-78 (2005). [Pub Med]





58) Mekkriengkrai, D., T. Sando, K. Hirooka, J. Sakdapipanich, Y. Tanaka, E.I. Fukusaki, and A. Kobayashi, "Cloning and Characterization of Farnesyl Diphosphate Synthase from the Rubber-Producing Mushroom Lactarius chrysorrheus." Biosci Biotechnol Biochem68(11): 2360-2368.(2004) [Pub Med]


57) Fujiwara, S., A. Yamanaka, K. Hirooka, A. Kobayashi, T. Imanaka, and E. Fukusaki, "Temperature-dependent modulation of farnesyl diphosphate/geranylgeranyl diphosphate synthase from hyperthermophilic archaea." Biochem Biophys Res Commun325(3): 1066-74.(2004) [Pub Med]


56) Fukusaki, E., S. Takeno, T. Bamba, H. Okumoto, H. Katto, S. Kajiyama, and A. Kobayashi, "Biosynthetic pathway for the c45 polyprenol, solanesol, in tobacco." Biosci Biotechnol Biochem68(9): 1988-90.(2004) [Pub Med]


55) Hasunuma, T., E. Fukusaki, and A. Kobayashi, "Expression of fungal pectin methylesterase in transgenic tobacco leads to alteration in cell wall metabolism and a dwarf phenotype." J Biotechnol111(3): 241-51.(2004) [Pub Med]


54) Hasunuma, T., S. Kuwabata, E. Fukusaki, and A. Kobayashi, "Real-time quantification of methanol in plants using a hybrid alcohol oxidase-peroxidase biosensor." Anal Chem76(5): 1500-6.(2004) [Pub Med]


53) Fukusaki, E., K. Kawasaki, S. Kajiyama, C.I. An, K. Suzuki, Y. Tanaka, and A. Kobayashi, "Flower color modulations of Torenia hybrida by downregulation of chalcone synthase genes with RNA interference." J Biotechnol111(3): 229-40.(2004) [Pub Med]


52) Fukusaki, E.-i., K. Ogawa, A. Okazawa, S.-i. Kajiyama, and A. Kobayashi, "A chitin-oligomer binding peptide obtained by screening of a phage display random peptide library and its affinity modulation corresponding to oxidation-reduction state." J. Mol. Cat. B28: 181-184.(2004) [Science Direct]


51) Bamba, T., E.-i. Fukusaki, Y. Nakazawa, and A. Kobayashi, "Rapid and high-resolution analysis of geometric polyprenol  homologues by connected octadecylsilylated monolithic silica columns in high-performance liquid chromatography." J. Sep. Science27(4): 293-296.(2004) [Pub Med]


50) Tang, L., A. Okazawa, Y. Itoh, E.-i. Fukusaki, and A. Kobayashi, "Expression of chlorophyllase is not induced during autumnal yellowing in Ginkgo biloba.Z. Naturforsch [C]59c: 415-420.(2004)  [Pub Med]





49) Marfori, E.C., S. Kajiyama, E. Fukusaki, and A. Kobayashi, "Phytotoxicity of the tetramic acid metabolite trichosetin."Phytochemistry62(5): 715 - 721.(2003) [Pub Med]


48) Kim, J.K., T. Shiraishi, E. Fukusaki, and A. Kobayashi, "Quantitation of formate by solid-phase microextraction and gas chromatography--mass spectrometry utilizing a [13C]formate internal standard." J Chromatogr A986(2): 313-7.(2003)[Pub Med]


47) Hirooka, K., T. Bamba, E.I. Fukusaki, and A. Kobayashi, "Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase." Biochem J370(Pt 2): 679-686.(2003) [Pub Med]


46) Hasunuma, T., E. Fukusaki, and A. Kobayashi, "Methanol production is enhanced by expression of an Aspergillus niger pectin methylesterase in tobacco cells." J Biotechnol106(1): 45-52.(2003) [Pub Med]


45) Fukusaki, E., T. Ikeda, D. Suzumura, and K. Akio, "A facile transformation of Arabidopsis thaliana using ceramic supported propagation system." J. Biosci. Bioeng.96(5): 503-505.(2003) [Pub Med]


44) Fukusaki, E., T. Nishikawa, K. Kato, A. Shinmyo, H. Hemmi, T. Nishino, and A. Kobayashi, "Introduction of the archaeal geranylgeranyl pyrophosphate synthase gene into Chlamydomonas reinhardtii chloroplast." J. Biosci. Bioeng.,95(3): 283-287.(2003) [Pub Med]


43) Bamba, T., E. Fukusaki, Y. Nakazawa, H. Sato, K. Ute, T. Kitayama, and A. Kobayashi, "Analysis of long-chain polyprenols using supercritical fluid chromatography and matrix-assisted laser desorption ionization time-of-flight mass spectrometry." J Chromatogr A995(1-2): 203-7.(2003) [Pub Med]


42) An, C.-I., A. Sawada, E.-i. Fukusaki, and A. Kobayashi, "A transient RNAi assay system using Arabidopsis protoplasts." Biosci. Biotech. Biochem.67(12): 2674-2677.(2003) [Pub Med]


41) Murayoshi, M., Y. Nakazawa, K. Gyokusen, E. Fukusaki, and A. Kobayashi, "Agrobacterium tumefaciens-mediated transformation of Eucommia ulmoides Oliver." Kyushu Journal of Forest Research (ed. Japanese)56: 176-177.(2003)


40) Miyabashira, A., K. Gyokusen, Y. Nakazawa, E. Fukusaki, T. Bamba, A. Kobayashi, and Y. Su, "Regeneration from stem and leaf of cis-rubber producing plant Periploca (Periploca sepium Bunge)." Bull. Kyushu. Univ. (ed. Japanese)84: 43-50.(2003)


39) Miyabashira, A., K. Gyokusen, T. Sando, E. Fukusaki, A. Kobayashi, Y. Nakazawa, T. Bamba, and Y. Su, "Introduction of foreign gene into Periploca  (Peroploca sepium Bunge)." Kyushu Journal of Forest Research (ed. Japanese)56: 178-179.(2003)





38) Sone, T., E. Nagamori, T. Ikeuchi, A. Mizukami, Y. Takakura, S. Kajiyama, E. Fukusaki, S. Harashima, A. Kobayashi, and K. Fukui, "A Novel Gene Delivery System in Plants with Calcium Alginate Micro-Beads." J. Biosci. Bioeng.94(1): 87-91.(2002) [Pub Med]


37) Shiraishi, T., Y. Kawamoto, T. Watanabe, E. Fukusaki, and A. Kobayashi, "Methylamine Treatment Changes the Allocation of Carbohydrate to Roots in Rice Plants." J. Biosci. Bioeng.94(5): 460-466.(2002) [Pub Med]


36) Marfori, E.C., T. Bamba, S. Kajiyama, E. Fukusaki, and A. Kobayashi, "Biosynthetic studies of the tetramic acid antibiotic trichosetin." Tetrahedron58: 6655-6658.(2002) [Science Direct]


35) Marfori, E.C., S. Kajiyama, E. Fukusaki, and A. Kobayashi, "Trichosetin, a novel tetramic acid antibiotic produced in dual culture of Trichoderma harzianum and Catharanthus roseus Callus." Z Naturforsch [C]57(5-6): 465-70.(2002) [Pub Med]


34) Dasman, S. Kajiyama, H. Kawasaki, M. Yagi, T. Seki, E. Fukusaki, and A. Kobayashi, "Paenibacillus glycanilyticussp. nov., a novel species that degrades heteropolysaccharide produced by the cyanobacterium Nostoc commune." Int J Syst Evol Microbiol52(Pt 5): 1669-74.(2002)  [Pub Med]


33) Dasman, S. Kajiyama, A. Okazawa, E. Fukusaki, and A. Kobayashi, "Purification and properties of an enzyme capable of degrading the polysaccharide of the cyanobacterium, Nostoc commune." Z Naturforsch [C]57(11-12): 1042-6.(2002) [Pub Med]


32) Bamba, T., E. Fukusaki, Y. Nakazawa, and A. Kobayashi, "In-situ chemical analyses of trans-polyisoprene by histochemical staining and Fourier transform infrared microspectroscopy in a rubber- producing plant, Eucommia ulmoidesOliver." Planta215(6): 934-9.(2002) [Pub Med]


31) An, C.I., S. Takekawa, A. Okazawa, E. Fukusaki, and A. Kobayashi, "Degradation of a peptide in pitcher fluid of the carnivorous plant Nepenthes alata Blanco." Planta215(3): 472-7.(2002) [Pub Med]


30) An, C.-I., E. Fukusaki, and A. Kobayashi, "Aspartic proteinases are expressed in pitchers of the carnivorous plantNepenthes alata Blanco." Planta, 214: 661-667.(2002) [Pub Med]





29) Fukusaki, E., T. Oishi, H. Tanaka, S. Kajiyama, and A. Kobayashi, "Identification of genes induced by taxol application using a combination of differential display RT-PCR and DNA microarray analysis." Z Naturforsch [C], 56(9-10): 814-9.(2001) [Pub Med]


28) Fukusaki, E., T. Hasunuma, S. Kajiyama, A. Okazawa, T.J. Itoh, and A. Kobayashi, "SELEX for Tubulin Affords Specific T-Rich DNA Aptamers." Bioorg Med Chem Lett11(22): 2927-2930.(2001) [Pub Med]


27) Fukusaki, E., T. Nakanishi, K. Ogawa, and A. Kobayashi, "A screening of phage display library for a neutral saccharide, 'chitin' in a medium containing ethanol." Electrochemistry69(12): 966-968.(2001)


26) Bamba, T., E. Fukusaki, S. Kajiyama, K. Ute, T. Kitayama, and A. Kobayashi, "High-resolution analysis of polyprenols by supercritical fluid chromatography." J Chromatogr A911(1): 113-7.(2001) [Science Direct]


25) Bamba, T., E. Fukusaki, S. Kajiyama, K. Ute, T. Kitayama, and A. Kobayashi, "The occurrence of geometric polyprenol isomers in the rubber-producing plant, Eucommia ulmoides Oliver." Lipids36(7): 727-32.(2001) [Pub Med]


24) Bamba, T., E.-i. Fukusaki, Y. Nakazawa, H. Sato, K. Ute, T. Kitayama, and A. Kobayashi, "Analysis of polyprenols by supercritical fluid chromatography." Kobunshi Ronbunshu (ed. Japanese)58(12): 642-649.(2001)


23) An, C.I., E. Fukusaki, and A. Kobayashi, "Plasma-membrane H+-ATPases are expressed in pitchers of the carnivorous plant Nepenthes alata Blanco." Planta212(4): 547-55.(2001) [Pub Med]





22) Tang, L., A. Okazawa, E. Fukusaki, and A. Kobayashi, "Removal of Magnesium by Mg-dechelatase Is a Major Step in the Chlorophyll-Degrading Pathway in Ginkgo biloba in the Process of Autumnal Tints." Z. Naturforsch.56: 923-926.(2000) [Pub Med]


21) Shiraishi, T., E. Fukusaki, and A. Kobayashi, "Formate dehydrogenase in rice plant: Growth stimulation effects of formate in rice plant." J. Biosci. Bioeng.89: 241-236.(2000) [Pub Med]


20) Shiraishi, T., E. Fukusaki, C. Miyake, A. Yokota, and A. Kobayashi, "Formate protects photosynthetic machinery from photoinhibition." J. Biosci. Bioeng.89: 564-568.(2000) [Pub Med]


19) Okazawa, A., H. Maeda, E. Fukusaki, and A. Kobayashi, "In Vitro Selection of Hematoporphyrin Binding DNA Aptamers." Bioorganic & Medicinal Chemistry Letters10: 2653-2656.(2000) [Pub Med]


18) Fukusaki, E., T. Ikeda, T. Shiraishi, T. Nishikawa, and A. Kobayashi, "Formate dehydrogenase gene of Arabidopsis thaliana is induced by formaldehyde and not by formi acid." J. Biosci. Bioeng.90: 691-693.(2000) [Pub Med]


17) Fukusaki, E., A. Saigo, S. Kajiyama, and A. Kobayashi, "An artificial plastic receptor that discriminates axial asymmetry." J. Biosci. Bioeng.90: 665-668.(2000) [Pub Med]


16) Fukusaki, E., T. Kato, H. Maeda, N. Kawazoe, Y. Ito, A. Okazawa, S. Kajiyama, and A. Kobayashi, "DNA aptamers that bind to chitin." Bioorg Med Chem Lett10(5): 423-5.(2000) [Pub Med]





15) Shiraishi, T., E. Fukusaki, S. Kajiyama, and A. Kobayashi, "A simple assay for formate dehydrogenase activity by gas chromatography-mass spectrometry." J Chromatogr A855(1): 337-40.(1999) [Pub Med]


14) Fukusaki, E., S. Satoda, S. Senda, and T. Omata, "Lipase-catalyzed kinetic resolution of 2,3-epoxy-1-tridecanol and its application to a facile synthesis of (+)-disparlure." J. Biosci. Bioeng.87(1): 103-104.(1999) [Pub Med]





13) Fukusaki, E., S. Satoda, S. Senda, and T. Omata, "Lipase-catalyzed kinetic resolution of 4-hydroxy-5-dodecynonitrile and its application to a facile synthesis of chafer beetle sex pheromone." J. Ferment. Bioeng.86(5): 508-509.(1998)[Science Direct]


12) Fukusaki, E., S. Satoda, H. Yuasa, S. Senda, T. Omata, M. Fukaya, and S. Wakamura, "Synthesis of the four possible stereoisomers of 21 methyl-8-pentatriacontene, the female contact sex pheromone of the yellow-spotted longicorn beetle, Psacothea hilaris." J. Ferment. Bioeng.85(1): 120-121.(1998) [Science Direct]





11) Marwani, E., A. Kobayashi, S. Kajiyama, E. Fukusaki, T. Nitoda, H. Kanzaki, and K. Kawazu, "Tectona grandis callus produces antibacterial triterpene acids not detected in the intact plant." Natural Product Sciences3(1): 75-80.(1997)


10) Fukaya, M., S. Wakamura, T. Yasuda, S. Senda, T. Omata, and E. Fukusaki, "Sex pheromonal activity of geometric and optical isomers of synthetic contact pheromone to males of the yellow-spotted longicorn beetle, Psacothea hilaris."Appl. Entomol. Zool.32: 654-656.(1997)





9) Uejima, A., T. Fukui, E. Fukusaki, T. Omata, T. Kawamoto, K. Sonomoto, and A. Tanaka, "Efficient kinetic resolution of organosilicon compounds by stereoselective esterification with hydrolases in organic solvent." Appl. Microbiol. Biotechnol.38: 482-486.(1993)





8) Fukusaki, E., S. Senda, Y. Nakazono, H. Yuasa, and T. Omata, "Preparation of carboxyalkyl acrylate by lipase-catalyzed regioselective hydrolysis of corresponding methyl ester." Bioorganic Medicinal Chem. Lett.2: 411-414.(1992)[Science Direct]


7) Fukusaki, E., S. Senda, Y. Nakazono, H. Yuasa, and T. Omata, "Large-scale preparation of (+)-disparlure, the gypsy moth sex pheromone, by a chemico-enzymatic procedure." J. Ferment. Bioeng.73: 284-286.(1992) [Science Direct]


6) Fukusaki, E., S. Senda, Y. Nakazono, H. Yuasa, and T. Omata, "Lipase-catalyzed kinetic resolution of 2,3-epoxy-8-methyl-1-nonanol, the key intermediate in the synthesis of the gypsy moth pheromone." J. Ferment. Bioeng.73: 280-283.(1992) [Science Direct]


5) Fukusaki, E., S. Senda, Y. Nakazono, and T. Omata, "Synthesis of the enantiomer of (Z)-5-(1-octenyl)oxacyclopentan-2-one, a sex pheromone of the cupreous chafer beetle, Anomala cuprea Hope." Biosci. Biotech. Biochem.56: 1160-1161.(1992)





4) ) Fukusaki, E., S. Senda, Y. Nakazono, and T. Omata, "Lipase-catalyzed kinetic resolution of methyl 4-hydroxy-5-tetradecynoate and its application to a facile synthesis of Japanese beetle pheromone." Tetrahedron,47: 6226-6230.(1991) [Science Direct]





3) Moriyama, H., E. Fukusaki, J.C. Crespo, A. Shinmyo, and H. Okada, "Structure and expression of genes coding for xylan-degrading enzymes of Bacillus pumilus." Eur. J. Biochem.166: 539-545.(1987) [Pub Med]





2) Panbangred, W., E. Fukusaki, E.C. Epifanio, A. Shinmyo, and H. Okada, "Expression of a xylanase gene of Bacillus pumilus in Escherichia coli and Bacillus subtilis." Appl. Microbiol. Biotechnol.22: 259-264.(1985) [Springer Link]





1) Fukusaki, E., W. Panbangred, A. Shinmyo, and H. Okada, "The complete nucleotide sequence of the xylanase(xynA) of Bacillus pumilus." FEBS Lett.171: 197-201.(1984) [Science Direct]